Interrelation between metabolic syndrome and chronic kidney disease
Keywords:
Obesidade, Resistência à Insulina, Insuficiência Renal Crônica,Abstract
Visceral obesity is commonly associated with metabolic syndrome (MS), diabetes mellitus type 2 (DM2) and arterial hypertension, two main causes of chronic kidney disease in the world. However, the role of MS in renal injury in non-diabetic patients has not been fully elucidated. Renal hemodynamic changes among obese individuals are precocious and marked by glomerular hiperfiltration, increased renal plasma flow and increased tubular sodium reabsorption. In addition, lipotoxicity, insulin resistance and inflammation appear to be involved in the kidney damage of obese subjects with MS. The understanding of the mechanisms involved in the MS-related kidney injury might contribute to implement strategies to prevent end-stage kidney disease, in this group of subjects.Downloads
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Published
2008-02-07
How to Cite
1.
Ezequiel DG, Costa MB, De Paula RB. Interrelation between metabolic syndrome and chronic kidney disease. HU Rev [Internet]. 2008Feb.7 [cited 2024May19];34(1):57-63. Available from: https://periodicos.ufjf.br/index.php/hurevista/article/view/35
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Section
Artigos de Revisão da Literatura
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