Oral microbiota versus oral mucositis during cancer treatment: a review

Authors

  • Izabella Henrichs Ribeiro
  • Júlia Ferigatto
  • Dionéia Evangelista Cesar
  • Rodrigo Luiz Fabri
  • Ana Carolina Morais Apolônio Instituto de ciências Biológicas. Departamento de Parasitologia, Microbiologia e Imunologia

DOI:

https://doi.org/10.34019/1982-8047.2020.v46.28995

Keywords:

Stomatites, Oral microbiota, Head and Neck Neoplams

Abstract

Introduction: Oral microbiota has been implicated on oral mucositis (OM) that occurs during cancer therapy, however without consensus. Objective: This study, aimed to establish, through a review, the association between oral microbiota and OM at head and neck cancer therapy (HNCT). Material and methods: The search of PubMed was performed considering 2008-2018 period, and the descriptors “oral mucositis” and “oral microbiota” in subheadings etiology and microbiology into the Medical Subject Heading (MeSH) “Head and Neck Neoplasms”. The conducting question was “Is there an oral dysbiosis during HNCT associated with OM?”. Results: 22 articles were selected under two steps of data extraction: articles that evaluated de oral microbiota during HNCT (n=13), and articles that also focused in OM (n=9). Conclusion: The evidence presented in the literature suggests associations of oral microbiota dysbiosis with the progression and worsening of radiation-induced OM. However, to define a microbial core for the disease, future standardized studies are required.

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References

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Published

2020-04-08

How to Cite

1.
Ribeiro IH, Ferigatto J, Cesar DE, Fabri RL, Apolônio ACM. Oral microbiota versus oral mucositis during cancer treatment: a review. HU Rev [Internet]. 2020Apr.8 [cited 2024Jun.30];46:1-9. Available from: https://periodicos.ufjf.br/index.php/hurevista/article/view/28995

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Section

Artigos de Revisão da Literatura

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