Regeneration of peripheral nerve by using coaptation with fibrin glue

Authors

  • Eduardo José Danza Vicente Universidade Federal de Juiz de Fora
  • Antonio de Castro Rodrigues Universidade de São Paulo
  • Priscila Cadima Vicente Universidade Estadual Paulista, UNESP, FMVZ, Botucatu, SP.
  • Claudia Helena Cerqueira Mármora Universidade Federal de Juiz de Fora, UFJF, CCS, Juiz de Fora, MG.
  • Paula Silva de Carvalho Chagas Universidade Federal de Juiz de Fora, UFJF, CCS, Juiz de Fora, MG.
  • Sueli Maria dos Reis Santos Universidade Federal de Juiz de Fora, UFJF, CCS, Juiz de Fora, MG.

Keywords:

Regeneração nervosa, Nervo fibular, Cola de fibrina,

Abstract

Many advances in the last decades have attempted to obtain a repair technique for lesions of peripheral nerves that results in better functional recovery of the structures innervated of such nerves. The main objective of this work is to compare the effectiveness of the coaptation with fibrin glue, derived from snake poison, in the repair of the peroneal nerve. Ten Wistar rats had their left peroneal nerve sectioned and repaired immediately with the glue, the right nerve serving as control. After ten weeks the peroneal nerve was collected for morphological analysis. In the nerves that were repaired with the glue, there were myelinated and unmyelinated regenerated nerve fibers, with a great amount of conjunctive tissue in the extracellular space. The nerve coaptation by the use of fibrin glue regenerated the lesion in the peroneal nerve, however the morphological pattern of the regeneration was compared to the peroneal nerve without lesion.

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Published

2008-02-01

How to Cite

1.
Vicente EJD, Rodrigues A de C, Vicente PC, Mármora CHC, Chagas PS de C, Santos SM dos R. Regeneration of peripheral nerve by using coaptation with fibrin glue. HU Rev [Internet]. 2008Feb.1 [cited 2024Nov.22];33(2):53-6. Available from: https://periodicos.ufjf.br/index.php/hurevista/article/view/61

Issue

Vol. 33 No. 2 (2007)

Section

Artigos Originais

License

Cessão de Primeira Publicação à HU Revista

Os autores mantém todos os direitos autorais sobre a publicação, sem restrições, e concedem à HU Revista o direito de primeira publicação, com o trabalho licenciado sob a Licença Creative Commons Attribution que permite o compartilhamento irrestrito do trabalho, com reconhecimento da autoria e crédito pela citação de publicação inicial nesta revista, referenciando inclusive seu DOI.

 

 

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