Quality of life and associated factors in women’s cervical cancer survivors
DOI:
https://doi.org/10.34019/1982-8047.2017.v43.2898Keywords:
Neoplasias do colo do útero. Sobreviventes. Qualidade de vida.Abstract
The treatment for cervical cancer can lead to late adverse effects such as sexual, bowel or urinary dysfunction; early menopause and lymphedema in the lower limb, which may have a negative impact on quality of life. The objective was to assess the quality of life of cervical cancer survivors, their associated factors, and to compare quality of life with a control group of women with no history of cancer. Women undergoing treatment for cervical cancer from a minimum of three months were included in the cancer group (n = 37). In the control group, which is population-based, were included women without history of cancer (n = 37). The quality of life was evaluated using the WHOQOL-bref and the sexual function by the Female Sexual Function Index. Clinical, therapeutic and socioeconomic variables were evaluated by a questionnaire developed by the authors. In comparison to control group, the cancer group presented higher proportion of women who lived without a partner and who considered the relationship with their partner as poor / regular. In addition, cervical cancer survivors have urinary, intestinal and sexual dysfunctions. Besides, the cancer group exhibited poor score in the "Physical" and "Social Relations" domains of WHOQOL-bref (p = 0.03 and 0.01, respectively). The factors independently associated with "Physical" domain were lower limb lymphedema and urinary retention, and with "Social Relations" domain were social support of friends and vaginal stenosis / shortening. The results suggest negative impact of the disease and its treatment on quality of life of cervical cancer survivors. Thus, it should be investigated the quality of life and the factors associated with it in order to improve patient’s care, which should be performed by multiprofessional team.
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ASHING-GIWA, K. T.; LIM, J. W.; TANG, J. Surviving cervical cancer: Does health-related quality of life influence survival? Gynecologic Oncology, v. 118, n. 1, p. 35-42, jul. 2010.
AZEVEDO e SILVA G, et al. Tendência da mortalidade por câncer nas capitais e interior do Brasil entre 1980 e 2006. Revista de Saúde Pública, v. 45, n. 6, p. 1009-18, dez. 2011.
BAE, H.; PARK, H. Sexual function, depression, and quality of life in patients with cervical cancer. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer, v.24, n.3, p.1277-1283, mar. 2016.
BARKER, C. L. et al. The impact of radiotherapy late effects on quality of life in gynaecological cancer patients. British Journal of Cancer, v. 100, n. 10, p. 1558-1565, may. 2009.
BASER, R. E.; CARTER, J.; LI, Y. Psychometric validation of the Female Sexual Function Index (FSFI) in cancer survivors. Cancer, v. 118, n. 18, p. 4606-4618, sep. 2012.
BERNARDO, B. C. et al. Disfunção sexual em pacientes com câncer do colo uterino avançado submetidas à radioterapia exclusiva. Revista Brasileira de Ginecologia e Obstetrícia, v. 29, n. 2, p. 85-90, fev. 2007.
BIFFI, R. G.; MAMEDE, M. V. Suporte social na reabilitação da mulher mastectomizada: o papel do parceiro sexual. Revista da Escola de Enfermagem da USP, v. 38, n. 3, p. 262-269, set. 2004.
BRASIL. Ministério da saúde. Instituto Nacional de Câncer José Alencar Gomes da Silva. Coordenação de Prevenção e Vigilância. Estimativa 2016: incidência de câncer no Brasil [Internet]. Rio de Janeiro: INCA; 2015 [citado em 2017 dez 7]. Disponível em: http://www.inca.gov.br/estimativa/2016/estimativa-2016-v11.pdf. Acesso em 07 dez. 2017.
CLEARY, V.; HEGARTY, J. Understanding sexuality in women with gynaecological cancer. European journal of oncology nursing: the official journal of European Oncology Nursing Society, v. 15, n. 1, p. 38-45, feb. 2011.
FLECK, M. P. A. O instrumento de avaliação de qualidade de vida da Organização Mundial da Saúde (WHOQOL-100): características e perspectivas. Ciência & Saúde Coletiva, v. 5, n. 1, p. 33-38, 2000.
FLECK, M. P. A. et al. Desenvolvimento da versão em português do instrumento de avaliação de qualidade de vida da OMS (WHOQOL-100). Revista Brasileira de Psiquiatria, v. 21, n. 1, p. 19-28, mar. 1999.
FERLAY, J. et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. International Journal of Cancer, v. 136, n. 5, mar. 2015.
FERNANDES, W. C.; KIMURA, M. Qualidade de vida relacionada à saúde de mulheres com câncer de colo uterino. Revista Latino-americana de Enfermagem, v. 18, n. 3, p. 360-367, may./jun. 2010.
FRUMOVITZ, M. et al. Quality of life and sexual functioning in cervical cancer survivors. Journal of Clinical Oncology: official journal of the American Society of Clinical Oncology, v. 23, n. 30, p. 7428-7436, oct. 2005.
GIRIANELLI, V.R., GAMARRA, C., AZEVEDO E SILVA, G. Os grandes contrastes na mortalidade por câncer do colo uterino e de mama no Brasil. Revista de Saúde Pública, v. 48, n. 3, p. 459-67, jun. 2014.
KHALIL, J. et al. Impact of cervical cancer on quality of life: beyond the short term (Results from a single institution). Gynecologic Oncology Research and Practice, v. 2, n. 7, p. 192-197, sep. 2015.
LE BORGNE, G. et al. Quality of life in long-term cervical cancer survivors: a population-based study. Gynecologic Oncology, v. 129, n. 1, p. 222-8, apr. 2013.
LEE, Y. et al. Comparison of Quality of Life and Sexuality between Cervical Cancer Survivors and Healthy Women. Cancer research and treatment: official journal of Korean Cancer Association, v. 48, n. 4, p. 1321-1329, oct. 2016.
PARK, S. Y. et al. Quality of Life and Sexual Problems in Disease-Free Survivors of Cervical Cancer Compared with the General Population. Cancer, v. 110, n. 12, p. 2716-2725, dec. 2007.
PENGA, V. M.; RUMIN, C. R. Vivências afetivas e o sofrimento de mulheres histerectomizadas. Omnia Saúde, v. 5, n. 2, p. 1-14, jul. 2008.
PFAENDLER, K. S. et al. Cervical cancer survivorship: long-term quality of life and social support. Clinical therapeutics, v. 37, n. 1, p. 39-48, jan. 2015.
OSANN, K.et al. Factors associated with poor quality of life among cervical cancer survivors: implications for clinical care and clinical trials. Gynecology Oncology, v. 135, n. 2, p. 266-72, nov. 2014.
RATNER, E. S. et al. Sexuality and intimacy after gynecological cancer. Maturitas, v. 66, n. 1, p. 23-26, may. 2010.
SCHLESSELMAN, J. J. Case-control studies: design, conduct, analysis. New York: Oxford University Press. 1982.
SHUANG, YE et al. A systematic review of quality of life and sexual function of patients with cervical cancer after treatment. International Journal Gynecology Cancer, v. 24, p. 1146-57, sep. 2014.
THE WHOQOL GROUP. The World Health Organization quality of life assessment (WHOQOL): position paper from the World Health Organization. Social Science & Medicine, v. 41, n. 10, p. 1403-1409, nov. 1995.
THIEL, R.R.C. et al. Tradução para português, adaptação cultural e validação do Female Sexual Function Index. Revista Brasileira de Ginecologia e Obstetrícia, v. 30, n. 10, p. 504-10, out. 2008.
TIWARI, P. et al. Breast and gynecologic cancer-related extremity lymphedema: a review of diagnostic modalities and management options. World Journal of Surgical Oncology, v. 11, p. 237-50, sep. 2013.
WENZEL, L. et al. Quality of life in long-term cervical cancer survivors. Gynecologic Oncology, v. 97, n. 2, p. 310-17, may. 2005.
WHITE, I. D. The Assessment and Management of Sexual Difficulties after Treatment of Cervical and Endometrial Malignancies. Clinical oncology (Royal College of Radiologists (Great Britain), v. 20, n. 6, p. 488-496, aug. 2008.
WIEGEL, M.; MESTON, C; ROSEN, R. The Female Sexual Function Index (FSFI): cross-validation and development of clinical cutoff scores. Journal of Sex & Marital Therapy, v. 31, n. 1, p. 1-20, jan./feb. 2005.
ZHOU, W. et al. Survey of cervical cancer survivors regarding quality of life and sexual function. Journal of Cancer Research and Therapeutics, v. 12, n. 2, p. 938-944, apr./jun. 2016.
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