General movements in newborn Infants with bronchopumonary dysplasia

Authors

  • Andrea Januario da Silva Unidade de Terapia Intensiva Neonatal, Hospital Regional João Penido, Juiz de Fora, Minas Gerais. Brasil. https://orcid.org/0000-0001-9945-1466
  • Laís Fonseca Côrte Real Faculdade de Medicina, Centro Universitário Presidente Antônio Carlos, Juiz de Fora, Minas Gerais. Brasil. https://orcid.org/0009-0006-4423-8952
  • Camila Bisconsin Castro Costa Faculdade de Medicina, Centro Universitário Presidente Antônio Carlos, Juiz de Fora, Minas Gerais. Brasil. https://orcid.org/0009-0004-5429-7767
  • Ana Carolina Trevisani Souza Faculdade de Medicina, Centro Universitário Presidente Antônio Carlos, Juiz de Fora, Minas Gerais. Brasil. https://orcid.org/0000-0001-6142-9327
  • Bianca Rodrigues de Oliveira Faculdade de Medicina, Centro Universitário Presidente Antônio Carlos, Juiz de Fora, Minas Gerais. Brasil. https://orcid.org/0009-0004-0517-1623
  • Anna Marcella Neves Dias2 Faculdade de Medicina, Centro Universitário Presidente Antônio Carlos, Juiz de Fora, Minas Gerais. Brasil.
  • Nathália Barbosa do E. Santo Mendes Faculdade de Medicina, Centro Universitário Presidente Antônio Carlos, Juiz de Fora, Minas Gerais. Brasil. https://orcid.org/0000-0001-9930-1222
  • Sônia Torres Horta de Araújo Faculdade de Medicina, Centro Universitário Presidente Antônio Carlos, Juiz de Fora, Minas Gerais. Brasil.

Keywords:

Newborn

Abstract

Introduction: Bronchopulmonary dysplasia (BPD) is an early risk factor for changes in neuropsychomotor development (NPMD), and its severity predisposes to functional, behavioral, sensory, and nutritional deficits in weight and height development in affected newborns. The General Movements Assessment (GMA) is an assessment tool for early identification of abnormal general movements in newborns, with high sensitivity and specificity for neurodevelopmental alterations. Thus, early identification of these changes allows for early interventions, improving the prognosis and quality of life of neonates in intensive care. Additionally, it enables the planning of actions at the three levels of health care, promoting prevention, protection, and recovery from these conditions. Objective: To analyze the quality of spontaneous movement of newborns (NBs) with bronchopulmonary dysplasia (BPD) compared to newborns without this diagnosis. Methods: An observational case-control study was conducted with users of the Unified Health System, with cases being newborns with BPD admitted to the Neonatal Intensive Care Unit. Premature newborns assessed by the General Movements Assessment (GMA) were included, and newborns who presented osteoarticular pathologies, congenital malformations of the Central Nervous System (CNS), use of vasoactive drugs and CNS depressants at the time of assessment were excluded. Data were analyzed by descriptive statistics, and to verify the association between general movements and BPD, the Chi-Square test or Fisher's exact test and binary logistic regression (α = 0.05) were used. Results: Of the 225 premature infants, 76 (33.8%) comprised the case group and 149 (66.2%) the control group. BPD and gestational age less than or equal to 32 weeks increased the chance of changes in spontaneous movement by 9.12 and 8.80 times, respectively. Conclusion: BPD increased the chance of changes in general movements, indicating that it negatively affected the CNS in the period of “preterm” and “wrinthing movements”.

 

Downloads

Download data is not yet available.

References

Silva AJ, Neves LAT, Frônio JS, Ribeiro LC. Factors related to motor developmental delay of newborns. J Hum Growth Dev. 2014; 24(3):320-7. DOI: 10.7322/jhgd.88970.

Monte L, Filho LV, Miyoshi MH, Rozov T. Displasia broncopulmonar. J Pediatr. 2005; 81(2):99-110. DOI: 10.1590/S0021-75572005000300004.

Higgins R, Jobe A, Koso-thomas M, Bancalari E, Viscardi R, Hartert T, Steinhorn et al. Bronchopulmonary dysplasia: executive summary of workshop. Jornal ou pediatrics. 2018. DOI: 10.1016/j.jpeds.2018.01.043.

Piscoya MDBV, Annes ALM, Silva GAA, Silva RM. Displasia broncopulmonar-Definição, fisiopatologia e tratamento: Revisão de literatura. Revista Inova Saúde [Internet]. 2017 [citado em 2026 mai. 04]; 6(1)93-106. Disponível em: https://periodicos.unesc.net/ojs/index.php/Inovasaude/article/view/2746/3312.

Linhares BQHS. A displasia broncopulmonar na unidade de terapia intensiva neonatal, uma revisão bibliográfica. Rev Ibero-Am Humanid Cienc Educ. 2023; 9(5):321-6. DOI:10.51891/rease.v9i5.9700.

Carvalho CG, Silveira RC, Procianoy RS. Lesão pulmonar induzida por ventilador em prematuros. Rev Bras Ter Intensiva 2013; 25(4):319-26. DOI: 10.5935/0103-507X.20130054.

Almeida AK. Avaliação do desenvolvimento neuromotor de prematuros de muito baixo peso nos primeiros meses de vida. Dissertação (Mestrado em Saúde Pública) – Universidade Federal do Ceará, Fortaleza, 2014; 110 p.

Nguyen k, Fitzgerard DA, Webb A, Bajuk B, Popat H. Neurodevelopmental outcomes of extremely preterm infants with bronchopulmonary dysplasia (BPD)- A retrospective cohort study. Paediatr Respir Rev. 2024; 50:23-30. DOI: 10.1016/j.prrv.2024.02.004.

Silva AJ, Souza FA, Feitosa MB, Frônio JS. Diagnóstico precoce de disfunção neuromotora por meio do método Prechtl de avaliação qualitativa dos general movements. In: Associação Brasileira de Fisioterapia Neurofuncional; Faria CDCM, Leite HR, organizadores. PROFISIO Programa de Atualização em Fisioterapia Neurofuncional: Ciclo 7. Porto Alegre: Artmed Panamericana; 2019. p. 10–62. (Sistema de Educação Continuada a Distância, v. 1).

Hadders-Algra M, Tacke U, Pietz J, Rupp A, Philipps H. Predictive value of the General Movements Assessment and Standardized Infant NeuroDevelopmental Assessment in infants at high risk of neurodevelopmental disorders. Dev Med Child Neurol. 2024 ;66(10):1361-68. DOI: 10.1111/dmcn.15901.

Aubert AM, Costa R, Johnson S, Adén U, Cuttini M, Esseboom CK, et al. Risk factors for cerebral palsy and movement difficulties in 5-year-old children born extremely preterm. Pediatr Res. 2024; 66(10):1361-68. DOI: 10.1038/s41390-022-02437-6.

Romijn M, Dhiman P, Finken MJJ, van Kaam AH, Katz T, Rottevvel J, et al. Prediction models for bronchopulmonary dysplasia in preterm infants: a Systematic Review and Metanalysis. The Journal of Pediatrics. 2023; 258:113370. DOI: 10.1016/j.jpeds.2023.01.024.

Domagalska-Szopa M, Szopa A, Serrano-Gomez ME, Hagner-Derengowska M, Behrendt, J. Identification of risk factors in pre-term infants with abnormal general movements. Front Neurol. 2022; 13:850877. DOI:10.3389/fneur.2022.850877.

Dutra LP, Rodrigues TD, Santos JS, Santana JL, Leite LS, Filgueiras ITC, et al. Habilidade motora grossa em lactentes prematuros segundo a Alberta Infant Scale. Rev Saúde Desenvolv; 2021.

Henke L, Kashani R, Yang D, Zhao T, Green O, Oslen L, et al. Simulated online adaptive magnetic resonance-guided stereotactic body radiation therapy for the treatment of oligometastatic disease of the abdomen and central thorax: characterization of potential advantages. Int J Radiat Oncol Biol Phys. 2016; 96(5):1078-86. DOI: 10.1016/j.ijrobp.2016.08.036.

Nascimento RM, Leite AJM, Almeida NMGS, Almeida PC, Silva CF. Determinantes da mortalidade neonatal: estudo caso-controle em Fortaleza, Ceará, Brasil. Cad Saúde Pública 2012; 28(3):559-72. DOI: 10.1590/S0102-311X2012000300016.

Zang FF, Yang H, Han Q, Cao JY, Tomantschger I, Krieber M, et al. Very low birth weight infants in China: the predictive value of the motor repertoire at 3 to 5months for the motor performance at 12months. Early Hum Dev. 2016; 100:27-32. DOI: 10.1016/j.earlhumdev.2016.03.010.

Hogeven M, Hooft L, Onland W. Hypothermia and adverse outcomes in very preterm infants. Pediatrics. 2025; 155(5):e2024069668. DOI: 10.1542/peds.2024-069668.

Lunsing RJ, Pardoen WFH, Hadders-Algra M. Neurodevelopment after moderate hyperbilirubinemia at term. Pediatr Res. 2013; 73(5):655-60. DOI:10.1038/pr.2013.28.

Almeida AKF, Carvalho EM, Sá FE, Frota LMCP. Avaliação comportamental de recém-nascidos prematuros com displasia broncopulmonar. Rev Fisioter S Func. 2014; 3(2):13-23. DOI: 10.36517/rfsf.v3i2.20589.

Tomantschger I, Herrero D, Einspieler C, Hamamura C, Voos MC, Marschik PB. The general movement assessment in non-European low- and middle-income countries. Rev. Saúde Pública. 2018; 52:6. DOI: 10.11606/S1518-8787.2018052000332.

Novak I, Morgan C, Adde L, Blackman J, Boyd RN, Brunstrom-Hernandez J, et al. Accurate Diagnosis and Early Intervention in Cerebral Palsy: Advances in Diagnosis and Treatment. JAMA Pediatri; 2017; 171(9):897-907. DOI: 10.1001/jamapediatrics.2017.1689.

Furtado AD, Pinto MVR, Rangel CC, Cruz LCH, Lopes JM, Carvalho M, et al. Confiabilidade da análise qualitativa da ressonância magnética do encéfalo em prematuros extremos. Radiol Bras. 2010; 43(6):375-8. DOI: 10.1590/S0100-39842010000600008.

Spittle AJ, Lee KJ, Spencer-Smith M, Lorefice LE, Anderson PJ, Doyle LW. Accuracy of Two Motor Assessments during the First Year of Life in Preterm Infants for Predicting Motor Outcome at Preschool Age. PLoS One. 2015; 10(5):e0125854. DOI: 10.1371/journal.pone.0125854.

Ruas JVD, Silva LC, Martins TM, Barboza ACF, Ribeiro, LM, Costa, et al. A importânica do pré natal na prevenção de complicações durante a gestação. Braz J Implantol Health Sci. 2024;6(1):1879-1887. DOI: 10.36557/2674-8169.2024v6n1p1879-1887.

Souza FA, Nogueira CCL, Silva AJ, Chagas PSC, Frônio JS. Preterm and writhing movements: is it possible to predict fidgety movements in preterm infants? J Perinatol. 2021; 41(10):2442-48. doi:10.1038/s41372-021-01064-z.

Downloads

Published

2026-08-11

How to Cite

1.
Silva AJ da, Real LFC, Costa CBC, Souza ACT, de Oliveira BR, Dias2 AMN, Mendes NB do ES, de Araújo STH. General movements in newborn Infants with bronchopumonary dysplasia . HU Rev [Internet]. 2026Aug.11 [cited 2026Aug.25];52:1-7. Available from: https://periodicos.ufjf.br/index.php/hurevista/article/view/52911

Issue

Vol. 52 (2026)

Section

Artigos Originais

License

Copyright (c) 2026 Andrea Januario da Silva, Laís Fonseca Côrte Real, Camila Bisconsin Castro Costa, Ana Carolina Trevisani Souza, Bianca Rodrigues de Oliveira, Anna Marcella Neves Dias2, Nathália Barbosa do E. Santo Mendes, Sônia Torres Horta de Araújo

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Cessão de Primeira Publicação à HU Revista

Os autores mantém todos os direitos autorais sobre a publicação, sem restrições, e concedem à HU Revista o direito de primeira publicação, com o trabalho licenciado sob a Licença Creative Commons Attribution que permite o compartilhamento irrestrito do trabalho, com reconhecimento da autoria e crédito pela citação de publicação inicial nesta revista, referenciando inclusive seu DOI.