Prevalência de leveduras do gênero Candida isoladas de hemocultura de pacientes hospitalizados
DOI:
https://doi.org/10.34019/1982-8047.2023.v49.40948Keywords:
Candida, Candidemia, Sepse, HemoculturaAbstract
Introduction: Bloodstream infection (BSI) by yeasts has Candida as its main genus. The main species that cause candidemia in Brazil are Candida albicans, Candida parapsilosis and Candida tropicalis, and C. albicans referred as the most prevalent. However, in recent decades, the prevalence of non-albicans Candida species (NAC) has increased and especially the emergence of Candida auris, which have mechanisms of resistance to the most used antifungals, characterizing a scenario of global concern. Objective: To assess the prevalence of Candida spp. in blood cultures of hospitalized patients, as well as the prevalence of the most isolated species and their distribution by hospital sectors. Material and Methods: This is an observational and retrospective study, of positive blood cultures for Candida spp. of patients admitted to a teaching hospital in the city of Juiz de Fora, Minas Gerais, from January 2021 to December 2022. Results: Among 3262 blood cultures analyzed, 1059 (32.46%) of which were positive. Of these, 1008 (95.18%) had bacterial growth and 51 (4.82%) had Candida spp. divided into, 20 (39.22%) C. albicans and 31 (60.78%) NAC. Of the NAC isolated, 14 were C. tropicalis (45.16%), 10 C. parapsilosis (32.26%), 3 C. glabrata (9.68%), 2 Candida kefyr (6.45%) and 2 Candida lusitaniae (6.45%). Of the 51 Candida spp. isolates, 25 (49.02%) were in the intensive care unit (ICU), 11 (21.57%) in the operating room and 15 (29.41%) were in the wards. Conclusion: Candida albicans is the main species related to candidemia in hospitalized patients, but species from the NAC group have shown high prevalence in blood culture isolates, especially in ICU patients.
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