Importance of BERA in the early neonatal period in newborns with risk factors for hearing loss.

Authors

  • Gabriella Fernandes Lima Residência Médica em Pediatria, Hospital Regional João Penido, Juiz de Fora, Minas Gerais, Brasil.
  • Rafael Fischer Oliveira Residência Médica em Pediatria, Hospital Regional João Penido, Juiz de Fora, Minas Gerais, Brasil.
  • Sílvia Paschoalini Azalim de Castro Residência Médica em Pediatria, Hospital Regional João Penido, Juiz de Fora, Minas Gerais, Brasil https://orcid.org/0000-0003-3487-7022
  • Carolina Ferreira Conti de Matos Residência Médica em Pediatria, Hospital Regional João Penido, Juiz de Fora, Minas Gerais, Brasil.

Keywords:

ABR; Newborns; Neonatology.

Abstract

Introduction: Neonatal hearing screening (NHS) was created to detect early alterations that may impact the hearing of newborns and infants, with the goal of referring them for accurate diagnosis and rehabilitation, if necessary. The ABR (Auditory Brainstem Response) is an important instrument in this auditory evaluation. Objective: To determine the main risk factors associated with altered ABR in infants treated in the maternity ward, pediatric ward, and neonatal ICU (NICU) of a reference hospital in the Zona da Mata region of Minas Gerais, in 2024. Material and Methods: Observational, cross-sectional, retrospective study conducted with 23 newborns with altered ABR. The variables evaluated included prematurity, length of stay in the NICU, time on mechanical ventilation, use of ototoxic medication, birth weight, congenital infections, postnatal bacterial or viral infections, and Apgar score at one and five minutes. Results: The main risk factors observed in neonates with altered ABR were: length of stay in the neonatal ICU greater than 5 days (91.3%), use of ototoxic medication (87%), and postnatal bacterial or viral infections (87%). Other factors such as low birth weight (65.2%), prematurity between 33 and 37 weeks (43.5%), and prematurity between 28 and 32 weeks (26%) were not as frequent, although they are important in other studies in the literature. Conclusion: The identification of risk factors for neonatal hearing loss reinforces the importance of screening and health policies aimed at preventing hearing loss in at-risk populations, since early detection allows for timely audiological intervention, potentially improving language development, cognition, and social skills.

Downloads

Download data is not yet available.

References

Fazito LT, Lamounier JA, Godinho RN, Melo MCB. Triagem auditiva neonatal e o diagnóstico precoce das deficiências auditivas na criança. Rev Med Minas Gerais [Internet]. 2008 [citado 2025 jan. 10]. Disponível em: https://www.rmmg.org/artigo/detalhes/1259.

Ministério da Saúde (BR). Recomendações técnicas para realização da triagem auditiva neonatal e seguimento assistencial. [Internet]. Brasília: DF; 2023 [citado 2025 jan. 10]. Disponível em: https://www.gov.br/saude/pt-br/acesso-a-informacao/participacao-social/consultas-publicas/2023/consulta-publica-recomendacoes-tecnicas-para-realizacao-da-triagem-auditiva-neonatal-e-seguimento-assistencial.

Brasil. Diretrizes de Atenção da Triagem Auditiva Neonatal [Internet]. Brasília: Ministério da Saúde; 2012 [citado 2025 jan. 20]. Disponível em: https://www.sbp.com.br/fileadmin/user_upload/2015/02/field_generico_imagens-filefield-description_69.pdf.

World Health Organization. Deafness and hearing loss [Internet]. Geneva: WHO; 2021 [citado 2025 jan 15]. Disponível em: https://www.who.int/news-room/fact-sheets/detail/deafness-and-hearing-loss.

Korver AM, van Zanten GA, Meuwese-Jongejeugd A, van Straaten HL, Oudesluys-Murphy AM. Auditory neuropathy in a low-risk population: a review of the literature. Int J Pediatr Otorhinolaryngol. 2012; 76(2):170-8. DOI: 10.1016/j.ijporl.2012.08.009.

Rajashekhar RP, Putta SD, Kothari A, Ingale M. The assessment of auditory function in high-risk neonates and infants using brainstem-evoked response audiometry (BERA). Cureus. 2024; 16(8):e66666. DOI: : 10.7759/cureus.66666.

Delgado CF, Simpson EA, Zeng G, Delgado RE, Miron O. Newborn auditory brainstem responses in children with developmental disabilities. J Autism Dev Disord. 2023; 53(2):776-88. DOI: 10.1007/s10803-021-05126-1.

Suflas R, Cox R, Viscardi RM, Leung JC. Risk factors for hearing screen failure in a single-family room neonatal intensive care unit. Am J Perinatol. 2025; 42(10):1272-80. DOI: 10.1055/a-2483-5788.

Reis FMFDS, Gonçalves CGO, Conto J, Iantas M, Lüders D, Marques J. Hearing assessment of neonates at risk for hearing loss at a hearing health high complexity service: an electrophysiological assessment. Int Arch Otorhinolaryngol. 2019; 23(2):157-64. DOI: 10.1055/s-0038-1648217.

Garinis AC, Kemph A, Tharpe AM, Weitkamp JH, McEvoy C, Steyger PS. Monitoring neonates for ototoxicity. Int J Audiol. 2018; 57(suppl 4):S41-S48. DOI: 10.1080/14992027.2017.1339130.

Arribas C, Decembrino N, Raffaeli G, Amodeo I, González-Caballero, Riaza M, et al. Ototoxic and nephrotoxic drugs in neonatal intensive care units: results of a Spanish and Italian survey. Eur J Pediatr. 2024; 183(6):2625-36. DOI: 10.1007/s00431-024-05467-w.

Rameshsankar S, Seethapathy J, Balakrishnan U. Ototoxic drug exposure and hearing loss in neonates: a scoping review. Am J Audiol. 2024; 33(4):1356-77. DOI: 10.1044/2024_AJA-24-00065.

Oliveira TDS, Dutra MRP, Nunes-Araujo ADDS, da Silva ARX, de Oliveira GBLL, Silva GJPC, et al. The prevalence of risk for hearing impairment in newborns with congenital syphilis in a newborn hearing screening program (NHS). Front Public Health. 2023; 11:1214762. DOI: 10.3389/fpubh.2023.1214762.

R M, Moideen SP, M M, MTP M, Afroze MKH. Audiological screening of high risk infants and prevalence of risk factors. Int J Contemp Pediatr. 2017; 4(2):507-11. DOI: 10.18203/2349-3291.ijcp20170699. 15. Sabbagh S, Amiri M, Khorramizadeh M, Iranpourmobarake Z, Nickbakht M. Neonatal hearing screening: prevalence of unilateral and bilateral hearing loss and associated risk factors. Cureus. 2021; 13(6):e15947. DOI:10.7759/cureus.15947.

Pehlajani Y, Shrivastava J, Mandraha S, Agrawal A, Datta M. Incidence and risk factors of hearing impairment in full-term neonatal intensive care unit (NICU) graduates: a cross-sectional observational study from Central India. Cureus. 2025; 17(8):e90399. DOI: 10.7759/cureus.90399.

Gama R, Alves S, Ribeiro L, Domingues B, et al. Neonatal hearing loss: outcomes of universal newborn hearing screening in a tertiary hospital center. Glob J Oto. 2019; 21(2):556058.

Neumann K, Chadha S, Tavartkiladze G, Bu X, White KR. Newborn and infant hearing screening facing globally growing numbers of people suffering from disabling hearing loss. Int J Neonatal Screen. 2019; 5(1):7. DOI: 10.3390/ijns5010007.

Vos B, Senterre C, Lagasse R; SurdiScreen Group; Levêque A. Newborn hearing screening programme in Belgium: a consensus recommendation on risk factors. BMC Pediatr. 2015; 15:160. DOI: 10.1186/s12887-015-0479-4.

Rahim TH. Hearing screening and risk factors of hearing loss: a systematic review. Open Access Maced J Med Sci. 2023; 11(F):259-64. DOI: 10.3889/oamjms.2023.10663.

Published

2026-08-18

How to Cite

1.
Lima GF, Oliveira RF, de Castro SPA, de Matos CFC. Importance of BERA in the early neonatal period in newborns with risk factors for hearing loss. HU Rev [Internet]. 2026Aug.18 [cited 2026Aug.25];52:1-6. Available from: https://periodicos.ufjf.br/index.php/hurevista/article/view/51625

Issue

Section

Artigos Originais

Similar Articles

1 2 > >> 

You may also start an advanced similarity search for this article.