Biocompatibility in pulpotomy: better material and alternatives to the MTA use - a systematic review and meta-analysis
DOI:
https://doi.org/10.34019/1982-8047.2023.v49.40598Keywords:
Pulp Capping and Pulpectomy Agents; Biocompatible materials; Pulpotomy.Abstract
Introduction: Vital pulp therapy is a treatment aimed at maintaining pulp vitality and tooth function. For pulpotomy, materials are chosen based on some fundamental characteristics, such as biocompatibility and bioactivity. Objective: The objective of this research is to identify the best material for use in pulpotomy considering the property of biocompatibility, through a systematic review of the literature and meta-analysis. Materials and Methods: The guiding question was: “What is the best agent for pulpotomy considering the biocompatibility property?”. A search was performed in the electronic databases MEDLINE/PubMed, SciELO, LILACS and Web of Science from inception to October 2020, using the following descriptors recognized by Medical Subject Headings (MeSH): “pulpotomy”, “pulp therapy”, “biomaterials”, “biocompatible materials'', “pulp capping agent”, “pulp capping materials”. The search was based on the acronym PICOS, developed in accordance with PRISMA and registered in the PROSPERO database (CRD42020191891). Risk of bias and meta-analysis were performed using Cochrane tools. Results: As a result, 358 studies were retrieved, 15 of them were admitted to qualitative analysis and six to quantitative analysis. The research evaluated clinical, radiographic and histological aspects, considering different follow-up periods, samples and methodologies. Several materials were found and MTA was the most studied. Although the qualitative results were inconclusive in relation to the best of them, it was possible to establish viable alternatives for MTA replacement. Conclusion: In conclusion, it was possible to obtain, through meta-analysis, that MTA is the most favorable material for use in pulpotomies in deciduous teeth.
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Copyright (c) 2023 Vitória Batista Clemente, Lara Martins Araújo, Vívian Gonçalves Carvalho Souza, Laísa Araújo Cortines Laxe, Mariana Simões Oliveira, Ana Carolina Morais Apolônio
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