Microbiota bucal versus mucosite oral durante o tratamento para o câncer: uma revisão

Autores

  • Izabella Henrichs Ribeiro
  • Júlia Ferigatto
  • Dionéia Evangelista Cesar
  • Rodrigo Luiz Fabri
  • Ana Carolina Morais Apolônio Instituto de ciências Biológicas. Departamento de Parasitologia, Microbiologia e Imunologia

DOI:

https://doi.org/10.34019/1982-8047.2020.v46.28995

Palavras-chave:

Estomatite, Microbiota bucal, Neoplasias de Cabeça e Pescoço

Resumo

Introdução: A microbiota bucal tem sido associada à mucosite oral que ocorre durante a terapia para o câncer apesar de não haver consenso.  Objectivo: Este estudo objetivou estabelecer por meio de uma revisão da literatura a associação entre a microbiota bucal e a mucosite oral durante a Terapia para o Câncer de Cabeça e Pescoço (TCCP). Material e métodos: Foi realizada uma busca na base de dados PubMed no período de 2008-2018 utilizando-se as palavras chave “oral mucositis” e “oral microbiota” nos subtítulos “etiology” e “microbiology” do descritor “Head and Neck Neoplasms” da base Medical Subject Heading (MeSH). A questão norteadora do estudo foi: “Ocorre uma disbiose durante a terapia para o câncer de cabeça e pescoço que esteja associada à mucosite oral?”. Resultados: 22 artigos foram selecionados em duas etapas de extração dos dados: artigos que avaliaram a microbiota bucal durante TCCP (n=13), e artigos que também focaram na mucosite oral (n=9). Conclusão: A evidência apresentada na literatura sugere associação de uma disbiose da microbiota bucal com a progressão e agravamento da mucosite oral induzida pela radiação. Entretanto, novos estudos padronizados são necessários para se definir o core microbiano para a doença.

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Publicado

2020-04-08

Como Citar

1.
Ribeiro IH, Ferigatto J, Cesar DE, Fabri RL, Apolônio ACM. Microbiota bucal versus mucosite oral durante o tratamento para o câncer: uma revisão. HU Rev [Internet]. 8º de abril de 2020 [citado 3º de dezembro de 2024];46:1-9. Disponível em: https://periodicos.ufjf.br/index.php/hurevista/article/view/28995

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