Bacterial vaginosis: clinical, epidemiologic and microbiological features

Autores

  • Didier Silveira Castellano Filho Faculdade de Ciências Médicas e da Saúde de Juiz de Fora – Suprema
  • Cláudio Galuppo Diniz Universidade Federal de Juiz de Fora
  • Vânia Lúcia Silva Universidade Federal de Juiz de Fora

Palavras-chave:

Bacterial vaginosis. Gardnerella vaginalis. Vaginal microbiota. Lactobacillus. Metronidazole.

Resumo

Bacterial Vaginosis (BV) is a polymicrobial clinical syndrome, whose etiolgy has not been fully understood which may occur in approximately 30% of the women of childbearing age.  It is result of the substitution of protective resident microorganisms as Labtobacillus spp. by opportunistic pathogenic bacteria such as Gardnerella vaginalis.  Patients with BV generally presents with copious, thin, homogeneous, milky, foul-smelling flow. Vaginal pH is greater than 4.5 and microscopy reveals bacteria-covered epithelial cells, termed “clue cells”. Around 50% of the patients are asymptomatic and the disease is associated with gynecologic complications, such as cervicitis, salpingitis, endometritis, post-operative infections and pelvic inflammatory disease; and obstetric complications, such as premature rupture of the membranes, preterm deliveries, chorioamniotitis and postpartum endometritis. Although the Nugent’s method is accepted as the gold standard for diagnosing BV, Amsel criteria are generally used for diagnosis in clinical practice.  The Papanicolaou method is a valid diagnostic option, chiefly when it yields a positive result (mean specificity 95% when compared to gold standard). G. vaginalis has been almost universally recovered from women with BV, plays an important role in the pathogenesis of the disease, besides it may be detected in about 50% of healthy women. According to the literature, first-line drugs for BV treatment worldwide are metronidazole and clindamycin. However, regional studies on G. vaginalis drug susceptibility patterns are needed faced the so fast growing bacterial antimicrobial resistance phenomenon.

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Biografia do Autor

Didier Silveira Castellano Filho, Faculdade de Ciências Médicas e da Saúde de Juiz de Fora – Suprema

Médico, professor da Faculdade de Ciências Médicas e da Saúde de Juiz de Fora – Suprema

Cláudio Galuppo Diniz, Universidade Federal de Juiz de Fora

Doutor em Microbiologia, Professor adjunto do Departamento de Parasitologia, Microbiologia e Imunologia.

Vânia Lúcia Silva, Universidade Federal de Juiz de Fora

Doutora em Microbiologia, Professora adjunta do Departamento de Parasitologia, Microbiologia e Imunologia.

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Publicado

2011-02-08

Como Citar

1.
Castellano Filho DS, Diniz CG, Silva VL. Bacterial vaginosis: clinical, epidemiologic and microbiological features. hu rev [Internet]. 8º de fevereiro de 2011 [citado 13º de agosto de 2022];36(3). Disponível em: https://periodicos.ufjf.br/index.php/hurevista/article/view/1107

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