HISTORY DIAGNOSIS ABOUT NEONATAL SCREENING FOR SICKLE CELL DISEASE

Abstract

 

The sickle cell disease is the most common inherited haematological disease in the world, and Sickle Cell Anemia is the most notorious of hematologic heritable changes in humans. This article presents the historical evolution of the process of creation and implementation of the Neonatal Screening in Brazil and parts of the world. The screening for newborns began in the 50 decade, but only from the decade of 60 the Programs of Neonatal Screening began be installed in several countries. The "Foot Test" is a strategy for the early diagnosis of congenital diseases that some are often imperceptible to the medical examination in the neonatal period, but that move adversely, leading to the emergence of sequels often irreversible. The sorting of hemoglobin is an important analysis for the prevention of sickle cell disease, which constitutes a Public Health problem in our country, after all it is estimated that in only Brazil there are approximately 10 million individuals heterozygous for the genes of hemoglobin.