Inflammatory process in asthma and allergic rhinitis

Authors

  • Rosa Maria de Carvalho
  • Fernando Monteiro Aarestrup

Keywords:

Asthma. Allergic rhinitis. Exhaled nitric oxide.

Abstract

Asthma and rhinitis are medical conditions that often coexist in the same patient, with strong impact on social life
and school performance of children and adolescents. The severity of both diseases is proportional, with the severity
of symptoms of allergic rhinitis related to the need for hospitalization in asthma attacks. These diseases have similar pathophysiological conditions that are characterized by inflammatory reaction that occurs in the airway mucosa,
resulting from complex interactions between inflammatory cells, structural and chemical mediators, regardless of
the intensity of the clinical manifestation. Monitoring the degree of inflammation is critical for the control of
asthma and rhinitis, and to that end, are considered ideal, in addition to clinical parameters, laboratory markers as
inflammatory cell counts in bronchial lavage and upper airway, as well as as fractional exhaled nitric oxide (FeNO).

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Published

2013-06-29

Issue

Section

Artigo de Revisão