O espectro clínico e laboratorial da doença de Alzheimer
Uma perspectiva neurológica
DOI:
https://doi.org/10.34019/1982-1247.2020.v14.30649Palavras-chave:
Demência, Doença de Alzheimer, Neurologia, MedicinaResumo
Esta revisão da literatura tem como objetivo mostrar recentes mudanças relacionadas ao diagnóstico da doença de Alzheimer (DA). O diagnóstico permanece clínico, no entanto, há um entendimento crescente de que biomarcadores específicos no líquido cefalorraquidiano e na neuroimagem molecular possam desempenhar um papel importante na definição etiopatogênica da doença. Os biomarcadores podem ser importantes para o diagnóstico nos estágios iniciais da DA. Considerando que a DA seja um processo fisiopatológico cerebral, a presença de biomarcadores específicos indica o diagnóstico de DA. Atualmente, o uso de biomarcadores é direcionado para pesquisa clínica e para o desenvolvimento de novas drogas.
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