Photostability of commercial sunscreens upon sunlight exposure

Autores/as

  • Rhaíssa Prado Departamento de Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais https://orcid.org/0000-0002-9753-5399
  • Filipe Soares Bertges Departamento de Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais
  • Sônia Aparecida Figueiredo Departamento de Ciências Farmacêuticas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Ribeirão Preto, São Paulo https://orcid.org/0000-0003-2549-4273
  • Maria José Vieira Fonseca Departamento de Ciências Farmacêuticas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Ribeirão Preto, São Paulo https://orcid.org/0000-0002-7123-4838
  • Guilherme Diniz Tavares Departamento de Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais https://orcid.org/0000-0001-6276-0994
  • Fernanda Maria Vilela Departamento de Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais https://orcid.org/0000-0001-6169-4550

DOI:

https://doi.org/10.34019/1982-8047.2020.v46.28819

Palabras clave:

Sunscreenig Agents, Ultraviolet Filters, Cosmetic Stability, Photodegradation

Resumen

Introduction: The use of sunscreens is recommended to reduce skin damage and prevent skin cancer. However, evidence has shown that sunscreen can undergo degradation processes induced by ultraviolet (UV) radiation which can lead to reduction or loss of photoprotective capacity, generation of free radicals and toxic intermediates which react with skin structures generating biological damage. Objective: To evaluate the photostability of four sunscreen formulations with Sun Protection Factor (SPF) 30 added by different chemical and physical UV filters. Material and Methods: Each product was exposed to solar radiation from 10 a.m. to 15 p.m. (UV index: 6.0). The areas under the curves (AUC) of the absorbance spectrum of the formulations before and after radiation exposure were used to calculate the ratio between the AUC before and after the solar radiation (AUCI). Results: Only two formulations, which presented the AUCI higher than 0.8, were considered photostable. Despite having the same SPF 30, formulations showed different absorption spectrum in regions of UVA1, UVA2 and UVB and the photostability of the products tested varied considerably. Conclusion: The development of photostable formulations is critical because degradation products of UV filters can act as photo-oxidants. Furthermore, increased exposure to UV radiation due to the reduction of the photoprotective capacity of unstable products increases the risk of burns and skin cancer.

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Publicado

2020-08-17

Cómo citar

1.
Prado R, Bertges FS, Figueiredo SA, Fonseca MJV, Tavares GD, Vilela FM. Photostability of commercial sunscreens upon sunlight exposure. HU Rev [Internet]. 17 de agosto de 2020 [citado 23 de noviembre de 2024];46:1-9. Disponible en: https://periodicos.ufjf.br/index.php/hurevista/article/view/28819

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