Intracranial Dysgerminoma

Authors

  • Adriana Souza Sérgio Ferreira UFJF
  • U-Thant Mendonça Lima Asconcer
  • Carlos Eduardo Amaral Pereira Silva Universidade vFederal de Juiz de Fora
  • Sandra Marcia Carvalho Ribeiro Costa Hospital Monte Sinai
  • Cibelle Ferreira Louzada Universidade Federal de Juiz de Fora
  • Sabrina Cristina Araújo Medanha Universidade Federal de Juiz de Fora

Keywords:

Disgerminoma. Neoplasias Embrionárias de Células Germinativas.

Abstract

Intracranial Dysgerminoma is a rare extragonadal germ cell tumor which originates itself at a extragonadal site.  It represents approximately 3 percent of intracranial tumors in children under the age of 15. For unknown reasons, these tumors are more frequent in Asian countries, where they account for 12 percent of  intracranial neoplasms. They show a peak in incidence between 10 and 14 years of age with a male predominance. We have reported a case of a 19 year-old patient who had been showing signs of diplopia and transitory parestesia of the left hand. He took brain magnetic resonance which identified nodule injuries in the right mesencephalus  and in the bilateral thalamic region as well. The histologic diagnosis was delayed due to the use of corticoid which contributed to the injury reduction preventing  access to the biopsy. After the interruption of the corticotherapy and injury regrowth, a biopsy was performed with the confirmation, by means of immunohistochemistry, of a brain  disgerminoma. The patient was submitted to a craniospinal radiotherapy, and a new magnetic resonance indicated a complete answer to the treatment done. <?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />

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Author Biographies

Adriana Souza Sérgio Ferreira, UFJF

Hospital Universitário da Universidade Federal de Juiz de Fora, Serviço de Oncologia

U-Thant Mendonça Lima, Asconcer

Hospital Asconcer, Serviço de radioterapia, Radiooncologista.

Carlos Eduardo Amaral Pereira Silva, Universidade vFederal de Juiz de Fora

Universidade Federal de Juiz de Fora, Departamento de Morfologia, neurocirurgião

Sandra Marcia Carvalho Ribeiro Costa, Hospital Monte Sinai

Hospital Monte Sinai, Centro de Investigação e diagnóstico em anatomia patológica, Patologista.

Cibelle Ferreira Louzada, Universidade Federal de Juiz de Fora

Acadêmica de medicina da UFJF

Sabrina Cristina Araújo Medanha, Universidade Federal de Juiz de Fora

Acadêmica de Medicina da UFJF

Published

2010-02-05

How to Cite

1.
Ferreira ASS, Lima U-TM, Silva CEAP, Costa SMCR, Louzada CF, Medanha SCA. Intracranial Dysgerminoma. HU Rev [Internet]. 2010Feb.5 [cited 2024Nov.21];35(3). Available from: https://periodicos.ufjf.br/index.php/hurevista/article/view/637

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