Comorbidities' influence on the occurrence of COVID-19 deaths in 2020: odds ratio in Amazonas, Brazil

Authors

DOI:

https://doi.org/10.34019/1982-8047.2022.v48.37689

Keywords:

COVID-19, Comorbidity, Mortality, Health Information Systems, Public Health Surveillance

Abstract

Introduction: The Sars-CoV-2 virus, from the coronavirus family, was discovered in December 2019 in China, in the city of Wuhan, the initial focus of the COVID-19 pandemic. COVID-19 caused several deaths worldwide and the presence of comorbidities was associated with an increase in these occurrences. Objective: use Data Science tools to analyze whether COVID-19 in Amazonas increased the risk of death in patients who developed Severe Acute Respiratory Syndrome (SARS) and concomitantly had some associated comorbidity. Material and methods: retrospective observational study of the paired case-control type based on SARS data available by the Ministério da Saúde in OpenDATASUS, using the Python programming language and the pandas library. Results: There were 17,924 cases of COVID-19 in 2020 in Amazonas, of these 5,882 patients died. Among the cases of deaths resulting from COVID-19, it was found that 68.74% had some associated comorbidity. When comparing groups according to exposure and occurrence of outcome, it was found that exposure to COVID-19 in patients with associated comorbidities increased the risk of death, except when Down syndrome was present. The most prevalent comorbidity among COVID-19 cases was chronic cardiovascular disease (47.84%) and the most lethal was chronic kidney disease (62.23%). Conclusion: this study demonstrated that the involvement by COVID-19 increased the chance of deaths in individuals with comorbidities who developed SARS in 2020 in Amazonas, in addition to show the negative impact of cardiovascular events on the progression of COVID-19.

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Author Biography

Ruy Roberto Porto Ascenso Rosa

Ruy Ascenso

References

Sun J, He WT, Wang L, Lai A, Ji X, Zhai X et al. COVID-19: epidemiology, evolution, and cross-disciplinary perspectives. Trends Mol Med. 2020; 26(5):483-95. doi: 10.1016/j.molmed.2020.02.008.

Organização Pan-Americana da Saúde. Folha informativa sobre COVID-19: histórico da pandemia de COVID-19. [citado em 2022 abr 06]. Washington: 2021. Disponível em: https://www.paho.org/pt/covid19/historico-da-pandemia-covid-19.

Ozma MA, Maroufi P, Khodadadi E, Köse Ş, Esposito I K et al. Clinical manifestation, diagnosis, prevention and control of SARS-CoV-2 (COVID-19) during the outbreak period. Infez Med. 2020; 28(2):153-65.

Sanyaolu A, Okorie C, Marinkovic A, Patidar R, Younis K et al. Comorbidity and its impact on patients with COVID-19. SN Compr Clin Med. 2020; 2(8):1069-76. doi: 10.1007/s42399-020-00363-4.

Ferrante L, Duczmal LH, Capanema E, Steinmetz WAC, Almeida ACL et al. Dynamics of COVID-19 in Amazonia: a history of government denialism and the risk of a third wave. Prev Med Rep. 2022; 26(101752):1-10. doi: 10.1016/j.pmedr.2022.101752.

Provost F, Fawcett T. Data science and its relationship to big data and data-driven decision making. Big Data. 2013; 1(1):51-9. doi: 10.1089/big.2013.1508.

Governo do Estado do Amazonas (BR). Manaus: Diário Oficial do Estado do Amazonas (DOEAM), de 18 de março de 2022, p. 26, 2022. [citado em 2022 abr 14]. Disponível em: https://www.jusbrasil.com.br/diarios/1173924061/doeam-18-03-2022-pg-26.

Anjorin AA, Abioye AI, Asowata OE, Soipe A, Kazeem MI et al. Comorbidities and the COVID-19 pandemic dynamics in Africa. Trop Med Int Health. 2021; 26(1):2-13. doi: 10.1111/tmi.13504.

Welty FK, Rajai N, Amangurbanova M. Comprehensive review of cardiovascular complications of coronavirus disease 2019 and beneficial treatments. Cardiol Rev. 2022; 30(3):145-57. doi: 10.1097/CRD.0000000000000422.

Tisminetzky M, Delude C, Hebert T, Carr C, Goldberg RJ, Gurwitz JH. Age, multiple chronic conditions, and COVID-19: a literature review. J Gerontol A Biol Sci Med Sci. 2022; 77(4):872-8. doi: 10.1093/gerona/glaa320.

Almamlouk R, Kashour T, Obeidat S, Bois MC, Maleszewski JJ et al. COVID-19-associated cardiac pathology at post-mortem evaluation: a collaborative systematic Review. Clin Microbiol Infect. 2022; S1198-743X(22):00160-4. doi: 10.1016/j.cmi.2022.03.021.

World Health Organization. Newsroom: fact sheets: the top 10 causes of death. [citado em 2022 abr 06]. Geneva: 2020. Disponível em: https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death.

Malik JA, Ahmed S, Shinde M, Almermesh MHS, Alghamdi S, Hussain A, Anwar S. The Impact of COVID-19 on comorbidities: a review of recent updates for combating it. Saudi J Biol Sci. 2022; 29(5):3586-99. doi: 10.1016/j.sjbs.2022.02.006.

Dell'Isola A, Kiadaliri A, Turkiewicz A, Hughes V, Magnusson K et al. The impact of first and second wave of COVID-19 on knee and hip surgeries in Sweden. J Exp Orthop. 2021; 8(1):1-7. doi: 10.1186/s40634-021-00382-7.

Published

2022-10-20

How to Cite

1.
Ascenso Rosa RRP, Lavareda Filho RM, Linhares JEB de S. Comorbidities’ influence on the occurrence of COVID-19 deaths in 2020: odds ratio in Amazonas, Brazil. HU Rev [Internet]. 2022Oct.20 [cited 2024Jul.18];48:1-8. Available from: https://periodicos.ufjf.br/index.php/hurevista/article/view/37689

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Section

Artigos Originais