Paracoccidioidomycosis in pregnancy: case report
DOI:
https://doi.org/10.34019/1982-8047.2019.v45.16954Keywords:
Paracoccidioidomycosis, pregnancy, lymphadenopathyAbstract
Introduction: paracoccidioidomycosis (PCM) is a systemic mycosis caused by the fungus Paracoccidioides brasiliensis. Brazil is considered endemic to this disease, affecting mainly adult rural male workers in constant contact with vegetation and soil. Objective: to report the clinical case of a 23-year-old pregnant woman, showing lymphadenomegaly in the cervical, supraclavicular and axillary spots, living in an urban area. Case report: the information was obtained by reviewing the medical files after the Free Informed Consent was signed, interviewing the patient along with pictures of the diagnostic methods the patient was submitted and literature review; a biopsy of the affected lymph node obtained the histopathological report of Paracoccidioidomycosis. Specific drug therapy was started on an in-patient basis, and the patient's clinical picture proceeded with involution. The follow up has been made on out-patient prenatal care, and has not observed, until now, maternal-fetal repercussions on the use of Amphotericin B, followed by clinical signs involution. Conclusion: It has been observed that paracoccidioidomycosis in pregnancy should be approached more aggressively in order to minimize or render serious maternal-fetal repercussions void.
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References
Fortes MR, Kurokawa CS, Marques SA, Miot HA, Marques MEA. Imunologia da paracoccidioidomicose. An Bras Dermatol. 2011; 86(3):516-25.
Ramos ESM, Saraiva E. Paracoccidioidomycosis. Dermatol Clin. 2008; 26:257-69.
Barrozo LV, Mendes RP, Marques SA, Benard G, Silva ME, Bagagli E. Climate and acute/subacute paracoccidioidomycosis in a hyper-endemic area in Brazil. Int J Epidemiol. 2009; 38:1642-9.
Palmeiro M, Cherubini K, Yurgel LS. Paracoccidioidomicose – Revisão da literatura. Scientia Medica. 2005;15(4):274-8.
Maluf MLF, Pereira SRC, Takahachi G, et al. Prevalência de paracoccidioidomicose: infecção determinada através de teste sorológico em doadores de sangue na região noroeste do Paraná, Brasil. Rev Soc Bras Med Trop. 2003; 36:11-6.
Bisinelli JC, Ferreira MLS. Doenças infecciosas: paracoccidioidomicose (blastomicose sul-americana). In: TOMMASI, AF. Diagnóstico em patologia bucal. 3ª ed. São Paulo: Pancast, 2002. p. 202-9.
Wanke B, Aidê MA. Paracoccidioidomicose. J Bras Pneumol. 2009; 35(12):1245-9.
Tarantino AB, Gonçalves AJR, Capone D, Aide MA, Lazera MS, Wanke B. Micoses Pulmonares. In: TARANTINO AB, editor. Doenças Pulmonares. Rio de Janeiro: Guanabara Koogan, 2002. p. 416-50.
Wanke B, Lazer MS, Capone D. Paracoccidioidomicose. In: Sociedade de Pneumologia e Tisiologia do Estado do Rio de Janeiro, AIDÉ MA, editors. Pneumologia aspectos práticos e atuais. Rio de Janeiro: Revinter, 2001. p. 147-52.
Pilmis B, Jullien V, Sobel J, Lecuit M, Lortholary O, Charlier C. Antifungal drugs during pregnancy: an updated review. J Antimicrob Chemother. 2015; 70:14–22.
Crum NF, Ballon-Landa G. Coccidioidomycosis in pregnancy: case report and review of the literature. Am J Med. 2006; 119(11):993.e-11-7.
Moudgal VV, Sobel JD. Antifungal drugs in pregnancy: a review. Expert Opin Drug Saf. 2003; 2:475–83.
Shikanai-Yasuda MA, Telles Filho FQ, Mendes, RP, Colombo AL, Moretti ML. Consenso em paracoccidioidomicose. Rev Soc Bra de Med Tropical. 2006; 39(3):297-310.
Franco M, Montenegro MR, Mendes, RP, Marques SA, Dillon ML, Mota NGS. Paracoccidioidomycosis: a recently proposed classification of its clinical forms. Reva Soc Bra de Med Tropical. 1987; 20:129-32.
BragaLFCO, Kasting G, Franke HJ. Placentite intervilosa Paraccoccidioidomicótica. Rev Bras Ginecol Obstet. 1989; 6:117-20.
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