TY - JOUR AU - Pellegrino, Flávia Lúcia Piffano Costa AU - Chagas, Thiago Pavoni Gomes AU - Alves, Maria Silvana AU - Carvalho-Assef, Ana Paula D’Alincourt AU - Chapeaurouge, Alexander AU - Asensi, Marise Dutra PY - 2018/10/15 Y2 - 2024/03/29 TI - Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) Applications in Bacteriology: brazilian contributions JF - HU Revista JA - HU Rev VL - 43 IS - 3 SE - Artigos de Revisão da Literatura DO - 10.34019/1982-8047.2017.v43.2859 UR - https://periodicos.ufjf.br/index.php/hurevista/article/view/2859 SP - 285 - 294 AB - <p><span lang="EN-US">Among its innumerous applications in Bacteriology, the </span><span lang="EN-US">M<span>atrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) technique is evolving</span> as a powerful tool for bacterial identification and antimicrobial resistance investigation. Publications have evaluated the MALDI-TOF MS performance in the identification of a series of bacterial pathogens, including the most common severe infectious agents, emergent pathogens involved with outbreaks of healthcare-associated infections, rare pathogens, and those whose isolation in culture media is difficult. <span>As compared to conventional methods of bacterial identification, MALDI-TOF MS has proven to be a fast, accurate and cost-effective technique. Currently, MALDI-TOF MS has been used in antimicrobial resistance studies, since it has shown to be an efficient tool in detecting</span> specific resistance mechanisms <span>in bacteria, such as beta-lactamases production, for example. </span></span><span lang="EN">Here, we describe the advances in this growing field of mass spectrometry applied to Bacteriology, including Brazilian contributions.</span></p> ER -